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Fig. 6 | BMC Genomics

Fig. 6

From: Genetic ancestry, admixture and health determinants in Latin America

Fig. 6

Ancestry-specific effects on gene expression. These results give an indication of how ancestry-enriched SNPs can impact health-related phenotypes by virtue of their gene regulatory effects. SNP-by-ancestry interactions were characterized using an expression quantitative trait loci (eQTL) approach. Examples of a African-specific and b European-specific eQTL are shown along with c eQTL shared between populations. d eQTL related to immune system and infectious disease found in the African and European populations are shown in a CIRCOS plot with links indicated between eQTLs and their regulated genes. e Examples of immune-related pathways that include multiple eQTL-regulated genes for African and/or European populations

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