Fig. 5

Pathway network and MAPK signaling. a The pathway network of interconnected signals was constructed based on the KEGG pathway database and literature. The calcium signaling pathway and MAPK signaling pathway were the two most interactive pathways. The calcium signaling pathway tightly interacted with pathways related to muscle contraction, and MAPK signaling interplayed with cell junction-related pathways. b The MAPK signaling pathway was enriched in the present study. The DEG are highlighted in red. The MAPK signaling pathway contains 4 distinct cascades, ERK1/2, JNK/MAPK, p38-MAPK, and ERK5. Few DEG were enriched in ERK1/2 signaling, but several DEG were enriched in JNK signaling