Fig. 3

Structure of κB and p53 binding motifs identified in analyzed genes. a The most probable common binding motifs revealed after analysis of ChIP-Seq data for all IR-induced peaks (±500 bp from the summits of p65 and p53 binding peaks). b Sequence and localization of the most probable motifs in the nearest vicinity of selected genes. Presented are binding regions identified by ChiP-Seq (upper inserts) and localization of analyzed PCR products (red and green bars) together with corresponding gene structures (exons and UTRs are marked with wide and narrow blue boxes, respectively); shown are distances from the Transcription Start Sites of the major transcript variants; red and green marks were used for RelA (p65) and p53, respectively