Fig. 2

Structural alignments between the models and its templates. a PDI model of T. gondii (blue) aligned with human PDI (red) with PDB code 3F8U. b RNR2 small subunit β model of T. gondii (blue) aligned with Plasmodium vivax RNR2 subunit β (red) with PDB code 2O1Z. c TgROP18 crystal structure (blue) with PDB code 4JRN; the missing regions modeled are shown in red. d TgCDPK1 crystal structure (blue) with PDB code 3SX9; the missing small regions modeled are shown in red. Green squares show active sites evaluated in each target proteins