Fig. 7
From: Coordinate regulation of long non-coding RNAs and protein-coding genes in germ-free mice
Genomic locations (a) and gene expression (b) of examples of lncRNA-PCG pairs that were differentially regulated by lack of gut microbiota in jejunum of CV and GF mice. (Note: Pathway analysis of PCGs paired with lncRNAs is shown in Additional file 2: Figure S4.) The P450 electron donor cytochrome p450 oxidoreductase (Por), the intestinal hydrogen peptide cotransporter Slc15a1, and the sodium-dependent purine transporter Slc28a2 are shown. The genomic locations for Slc5a12 and Slc28a2 are shown in Fig. 6. Expression of lncRNAs and paired PCGs were plotted using mean FPKM ± S.E., and asterisks (*) indicate statistically significant differences between enterotypes of mice (FDR-BH < 0.05)