Fig. 1
From: Helmsman: fast and efficient mutation signature analysis for massive sequencing datasets
Performance comparison for generation of the mutation spectra matrix by different programs. For Helmsman and three other mutation signature analysis tools (SomaticSignatures, deconstructSigs, and signeR), we measured the maximum memory usage in megabytes (a) and processing time in seconds (b) required to generate the 2504 × 96 mutation spectra matrix from a VCF file containing 15,971 SNVs in 2504 samples from the 1000 Genomes project