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Fig. 4 | BMC Genomics

Fig. 4

From: Genetic diversity of Escherichia coli in gut microbiota of patients with Crohn’s disease discovered using metagenomic and genomic analyses

Fig. 4

Clustering of the metagenomes and E. coli genomes based on a unified representation of the accessory gene presence profile. Clustering is performed by the accessory OG profiles (binary metric, average linkage). Colour legend: black - genomes of pathogenic strains, green - commensal, red - Russian CD, blue - USA treatment-naive CD, orange - Spanish CD (remission), grey - healthy populations and other known E. coli genomes (details are in Additional file 1: Table S9)

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