Fig. 5
From: GOPHER: Generator Of Probes for capture Hi-C Experiments at high Resolution
Simple patched viewpoints. In the first run of simple viewpoint creation, only digests that contain the TSS are selected. This may result in viewpoints that are not well centered at the TSS. Such viewpoints can be manually revised by selecting adjacent digests in upstream or downstream direction (Fig. 4c). GOPHER provides an option referred to as “patching“ that automates this process. If the score of a simple viewpoint is below 0.6, GOPHER will add the appropriate adjacent digest if possible