Table 5 Genes Oppositely Regulated by Circadian Misalignment and Aging
gene name | week 3 log2FC | week 3 p-adj | aging log2FC | aging p-adj | function |
|---|---|---|---|---|---|
--Downregulated with CCM; Upregulated with Aging-- | |||||
 CG3739 | −0.90 | 3.70E-13 | 0.20 | 2.38E-01 | dipeptidyl-peptidase activity; serine-type peptidase activity |
 CG18609 | −0.80 | 7.72E-13 | 0.56 | 4.94E-04 | fatty acid elongase activity |
 CG34180 | −0.75 | 1.46E-03 | 0.50 | 1.04E-01 | unknown |
 CG10960 | −0.67 | 1.49E-06 | 0.51 | 4.81E-03 | carbohydrate:proton symporter activity; glucose transmembrane transporter activity |
 CG11741 | −0.56 | 4.57E-02 | 0.67 | 3.26E-02 | unknown |
 b6 | −0.55 | 4.23E-02 | 0.38 | 1.79E-01 | unknown |
 Uro | −0.54 | 2.75E-02 | 0.57 | 3.79E-02 | urate oxidase activity |
 rost | −0.51 | 2.96E-02 | 0.35 | 1.14E-01 | unknown |
 CG4607 | −0.48 | 7.35E-03 | 0.58 | 1.96E-04 | carbohydrate:proton symporter activity; glucose transmembrane transporter activity |
 CG15096 | −0.46 | 9.90E-02 | 0.48 | 4.42E-02 | transmembrane transporter activity |
 CG9459 | −0.35 | 8.04E-02 | 0.71 | 1.34E-03 | fatty acid elongase activity |
 CG14464 | −0.33 | 9.77E-02 | 0.46 | 1.09E-02 | unknown |
--Upregulated with CCM; Downregulated with Aging-- | |||||
 CG5804 | 0.51 | 7.70E-03 | −0.36 | 1.68E-01 | fatty-acyl-CoA binding |
 CG5767 | 0.45 | 4.87E-02 | −0.65 | 6.97E-03 | unknown |
 CG34330 | 0.41 | 3.14E-02 | −0.22 | 2.57E-01 | unknown |
 AsnS | 0.37 | 7.58E-02 | −0.36 | 8.08E-02 | asparagine synthase (glutamine-hydrolyzing) activity; protein homodimerization activity |