Table 9 Top Regulator Effect Networks generated from CpG DNA and poly(I:C)-stimulated Bomac cell line after 6 h of stimulation. (A) CpG DNA, (B) poly(I:C). Data were analyzed in IPA (QIAGEN Inc., https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis
| Â | Regulators | Diseases & Functions | Consistency Score |
|---|---|---|---|
A | Cg,HIF1A,miR-3202 (miRNAs w/seed GGAAGGG) | cell movement of embryonic cell lines | 4.025 |
BMP6,Ins1,MYC | lymphoproliferative disorder | 3.328 | |
ERG,RXRA | Growth Failure | 2.121 | |
miR-4525 (and other miRNAs w/seed GGGGGAU) | Growth Failure | −4.082 | |
IGF1 | Growth Failure | −5.367 | |
B | Interferon alpha | Replication of viral replicon | 3.606 |
Interferon alpha | Viral life cycle | 3.606 | |
lipopolysaccharide | Replication of viral replicon | 3.464 | |
PRL | Immune response of cells | 3.357 | |
IFNA2 | Replication of viral replicon | 3.317 |