Table 2 TF-mediated regulation of genes via induced enhancers
TF Motifs | # overlapping enhancers | # target DEGs |
|---|---|---|
AP-1 (FOSL1::JUNB, FOSL2::JUNB, JUNB, FOSL2, FOSL1) | 128 (49.8%) | 180 (68.4%) |
NF-kB (REL, RELA, NFKB2) | 117 (45.5%) | 157 (59.7%) |
RBPJ | 117 (45.5%) | 160 (60.8%) |
IRF1 | 88 (34.2%) | 126 (47.9%) |
Nfe2l2 | 54 (21%) | 86 (32.7%) |
JDP2 | 53 (20.6%) | 92 (35%) |
Total (12 motifs) | 229 (89.1%) | 250 (95.1%) |