Fig. 3From: A mathematical model as a tool to identify microRNAs with highest impact on transcriptome changesDesign of matrix C. Each line joining a mRNA and a miRNA symbolizes the interaction of a miRNA with a target motif in a transcript (one line is one interaction, dashed line for miRNA1, solid line for mRNA2). Coefficients cji are obtained based on miRanda3.3a [34], TargetScan [35], RNAhybrid [36], and NucleoSeq [37] algorithms (Table 1)Back to article page