Table 6 Features characterizing mRNAs with good or poor fit to the model, with Me45 cells as reference
From: A mathematical model as a tool to identify microRNAs with highest impact on transcriptome changes
Feature | Me45 Cells: Average over | Good vs. poor fit p-value | ||||
|---|---|---|---|---|---|---|
Good fit | Poor fit | Me45 | K562 | HCT116+/+ | HCT116−/− | |
3’-UTR average length [nucleotides] | 1466.3 | 1229.2 | 7.23 × 10 –06 b | 0.007 b | 0.106 | 0.117 |
Average turnover time [h] | 7.912 | 8.766 | 0.0030 b | 0.027 b | 0. 609 | 0.829 |
Average number of ARE consensus motifs/gene | 0.217 | 0.263 | 0.0291 b | 0.791 | 7.19 × 10 –05 b | 0.004 b |
MYC response elements / gene | 1.434 | 1.561 | 0.0004 b | 0.003 b | 0.079 | 0.030 b |