Fig. 1From: In silico characterization of multiple genes encoding the GP63 virulence protein from Leishmania braziliensis: identification of sources of variation and putative roles in immune evasionGP63 general gene features. The scheme highlights conserved elements found on most GP63 sequences, such as the signal peptide, propeptide, zinc-binding motif [8], multiple cysteine residues, the GPI anchor site and a nearly universally conserved motif of seven consecutive amino acids we named KDELMAP. The PCR strategy used to amplify the GP63 genes is also shown with products varying from 1 Kb (up to the KDELMAP region) and 1,6 Kb (finishing on the GPI anchor site)Back to article page