Fig. 3
From: Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding
a The distribution of the dispersion of the barcode log fold changes (TRAIL-R antibody treated vs untreated) at day 14 for each sgRNA is shown for each of the four clonal Cas9 lines. For each sgRNA, the interquartile range (IQR) of the barcodes log fold-changes was computed. b Barcode subsampling across the four clonal Cas9 lines. The x-axis shows the fraction of barcodes sampled for each sgRNA. The y-axis shows the rank of four genes (A) TNFRSF10B, B) CASP8, C) STK35, D) BAK1) in the MAGeCK output obtained from the subsampled datasets