Table 1 Simulation based performance comparison between the distance-type data and the count-type data (for the detection power; W is the bin size)
From: A distance-type measure approach to the analysis of copy number variation in DNA sequencing data
p-value cutoff | Distance-type data | Count-type data | ||
|---|---|---|---|---|
W = 25,000 bps | W = 10,000 bps | W = 5000 bps | ||
Region length L = 50,000 bps | ||||
 0.05 | 28.9% | 0 | 12.8% | 16.1% |
 0.01 | 12.8% | 0 | 0.1% | 7.1% |
 0.001 | 3.4% | 0 | 0 | 2.1% |
 0.0001 | 0.8% | 0 | 0 | 0.3% |
 0.00001 | 0.1% | 0 | 0 | 0 |
 0.000001 | 0 | 0 | 0 | 0 |
Region length L = 200,000 bps | ||||
 0.05 | 73.8% | 62.4% | 68.2% | 64.5% |
 0.01 | 59.4% | 42.8% | 50.3% | 52.9% |
 0.001 | 40.5% | 20.2% | 30.5% | 34.5% |
 0.0001 | 26.6% | 0 | 14.3% | 24.1% |
 0.00001 | 15.3% | 0 | 8.0% | 11.3% |
 0.000001 | 8.7% | 0 | 1.6% | 5.7% |
Region length L = 1,000,000 bps | ||||
 0.05 | 97.6% | 97.0% | 96.8% | 96.6% |
 0.01 | 94.7% | 94.0% | 94.1% | 94.0% |
 0.001 | 89.7% | 88.6% | 90.1% | 90.6% |
 0.0001 | 85.3% | 83.0% | 84.9% | 85.9% |
 0.00001 | 80.7% | 72.1% | 80.2% | 80.7% |
 0.000001 | 75.8% | 62.8% | 72.7% | 75.7% |