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Fig. 3 | BMC Genomics

Fig. 3

From: Proteome profiling of triple negative breast cancer cells overexpressing NOD1 and NOD2 receptors unveils molecular signatures of malignant cell proliferation

Fig. 3

Subcellular localization and cellular component distribution. Subcellular localization and interactions of differentially expressed proteins in groups NOD1 (HS578T/NOD1) (a) and NOD2 (HS578T/NOD2) (b), obtained via Qiagen Ingenuity® Pathway Analysis (IPA®). Direct protein interactions are represented by continuous lines, while indirect relationships are represented by dotted lines. Gene Ontology (GO) cellular component term assignment for NOD1 (c) and NOD2 (d) experimental groups, obtained via EnrichR (http://amp.pharm.mssm.edu/Enrichr) membership analysis (GO database version 2017b). The length of the bar represents the statistical significance of the combined score in Fisher exact test for that specific gene-set or term. In addition, the brighter the color, the more significant that term is. Top supporting protein evidence for each GO cellular component term presented at the left of horizontal bars

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BMC Genomics

ISSN: 1471-2164

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