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Fig. 4 | BMC Genomics

Fig. 4

From: Risk-modeling of dog osteosarcoma genome scans shows individuals with Mendelian-level polygenic risk are common

Fig. 4

Transcription factor binding site analysis of osteosarcoma GWA candidate genes. Transcription factor binding sites shared by OS GWA candidates (n = 13), OS somatically-mutated genes (n = 23) and genes with germ line size-association (n = 7; implemented in DAVID). Legend: 1PubMed search with terms “osteosarcoma” or “bone or osteoblast, not marrow”; 2Multiplicity corrected p-value and False Detection Rate (FDR) in DAVID analysis; 3IKZF1 is a canine OS GWA candidate; color scale is yellow high, blue low, 4except the top 2 genes, which have dominant effects (NFAT and P53, gray)

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BMC Genomics

ISSN: 1471-2164

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