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Fig. 2 | BMC Genomics

Fig. 2

From: Linear models enable powerful differential activity analysis in massively parallel reporter assays

Fig. 2

Variability of MPRA activity measures depends on element copy number. For multiple publicly available datasets we compute activity measures of putative regulatory element as the log2 ratio of aggregated RNA counts over aggregated DNA counts. Each panel shows the relationship between variability (across samples) of these activity measures and the average log2 DNA levels (across samples). Smoothed relationships are lowess curves representing the local average variability. The last plot shows all lowess curves on the same figure

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