Fig. 3

a Comparison of Blast Ring Image Generated for E. coli O157:H7 strain NADC 6564 (black innermost ring) with similar images generated for other lineage I (EDL933, red ring; Sakai, purple ring), lineage II (FRIK2533, green ring), and lineage I/II (TW14359, blue ring) E. coli O157:H7 strains, non-O157 strains (O111, yellow ring; O26, blue ring) and a non-pathogenic E. coli K12 strain MG1655 (outermost orange ring). The colored legend to the right shows the degree of nucleotide sequence homology between the sequences of strain NADC 6564 to other O157:H7 and non-O157:H7 E. coli strains. The white gaps in rings represent genomic regions that are missing in the corresponding genomes compared to strain NADC 6564. Locations of genomic islands (GI) and phage or phage-like elements (P) are indicated on the two outer rings. b Magnified picture of the 39-kb insertion element (IE) identified in the chromosome of E. coli O157:H7 strain NADC 6564 but lacking in the chromosomes of other strains listed in the legend on the right side panel. This element is bounded at both ends by a 56 bp repeat sequence (not shown in the figure) and inserted at the tRNA-leu gene in the chromosome. The outer most ring shows relative locations of various genes and their encoded proteins and associated functions