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Fig. 1 | BMC Genomics

Fig. 1

From: Differential isoform expression and alternative splicing in sex determination in mice

Fig. 1

Differentially expressed genes (DEG) in male and female gonads at E11 and E12 and analysis of gene clustering. (a) Quantitative PCR analysis of Sry expression in male embryonic day 11 and 12.5 (E11-E12.5) gonads. Biological triplicate results are presented as mean ± SEM. Bars with different superscripts differ significantly (ANOVA, P < 0.05). (b) Diagram showing the genes upregulated in E11 and E12 male and female gonads. In brackets is the number of specific genes as observed in graphs C to F. (c-f) Venn diagrams showing DEGs in E11 and E12 male and female gonads. Subset of genes represent specific upregulated genes in males at E11 (c) and E12 (d), and in females at E11 (e) and E12 (f). Analysis with Cluster Locator [15] of clustering of genes upregulated in E11 (g) and E12 (h) male and female gonads

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