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Table 3 Comparison of mean number of mapped reads in samples with multiple and single HPV plasmids

From: Universal human papillomavirus typing by whole genome sequencing following target enrichment: evaluation of assay reproducibility and limit of detection

HPV

Poola (Mean ± SDb)

Single (Mean ± SD)

p-value

HPV11

9313 ± 597

9571 ± 468

0.68

HPV16

8796 ± 313

7797 ± 626

0.22

HPV31

9010 ± 651

9832 ± 501

0.292

HPV45

14,322.5 ± 1060

16,401 ± 855

0.164

HPV52

11,272 ± 967

12,393 ± 1119

0.400

HPV6

7097 ± 311

7011 ± 378

0.827

HPV18

12,566 ± 874

12,555 ± 943

0.990

HPV33

12,231 ± 859

10,699 ± 726

0.194

HPV58

12,617 ± 991

8509 ± 725

0.042

  1. aPool 1 included HPV 11, 16, 31, 45, and 52; pool 2 included HPV 6, 18, 33, and 58
  2. bMean and SD were calculated based on 2 replicates for each sample