The identification of differentially expressed genes between extremes of placental efficiency in maternal line gilts on day 95 of gestation

Table 4 Significant correlations between fetal/utero-placental measurements and DEG in high PE compared to low PE placentas

Correlation Data^a			DEG Data^b
Measurement* Gene	Correlation	FDR P-value	Gene Symbol	Protein	Molecular Function	log FC	FDR P-value
PW*gene1223	0.82	0.0214	GCOM1	Myocardial Zonula Adherens Protein	N/A	−0.43	0.0769
PE*gene12188	0.81	0.0214	LOC100156118	N/A	N/A	0.63	0.0484
PE*gene24847	0.81	0.0214	TMEM199	Transmembrane Protein 199	N/A	0.29	0.0421
PW*gene19656	0.78	0.0257	LOC100739517	ATP-Binding Cassette Sub-Family G Member 2	N/A	−0.61	0.0144
PW*gene13353	0.77	0.0257	TOX3	TOX High Mobility Group Box Family Member 3	Chromatin binding, Phosphoprotein binding, Protein homodimerization activity, Estrogen response element binding	−1.41	0.0183
PW*gene19659	0.76	0.0257	ABCG2	ATP-Binding Cassette Sub-Family G Member 2	ATP binding, ATPase activity coupled to transmembrane movement of substance, Cholesterol transporter activity	−0.77	0.0039
PE*gene6367	0.76	0.0428	PCDHB1	Protocadherin Beta-1 Isoform X2	Calcium ion binding	2.42	0.0030
PW*gene26368	−0.76	0.0257	RAB6B	Ras-Related Protein Rab-6B	GTP binding, GTPase activity, Myosin V binding	0.86	0.0084

^aPW Placental weight, PE placental efficiency, FDR P-value false discovery rate adjusted P-value, level of significance P < 0.05. ^bDEG Differentially expressed genes, N/A not available, log₂FC log₂ fold change, FDR P-value false discovery rate adjusted P-value, level of significance P < 0.10

ISSN: 1471-2164