Prioritizing candidate genes for fertility in dairy cows using gene-based analysis, functional annotation and differential gene expression

Table 2 Candidate genes identified by gene-based analysis

QTL	Official Gene name	Location	-log₁₀(P)
1: 69742415	DIRC2	67,722,242–67,810,789	56.38
	SEMA5B	67,840,125–67,878,028	50.97
	PDIA5	68,012,078–68,101,852	47.22
	SEC22A	68,170,572–68,232,640	23.42
	ADCY5	68,263,141–68,420,954	61.35
	MYLK	68,580,144–68,667,822	47.83
	ROPN1	68,954,525–68,989,623	22.27
	KALRN	69,248,613–69,724,961	62.48
	UMPS	69,732,778–69,782,823	31.65
	ITGB5	69,801,844–69,899,676	40.59
	HEG1	70,027,330–70,106,415	44.68
	SLC12A8	70,126,992–70,250,895	30.26
	UBXN7	71,542,376–71,573,340	33.56
	RNF168	71,629,579–71,653,254	45.44
1: 140785028	PSMG1	140,726,628–140,739,236	27.92
1: 140785028	BRWD1	140,741,647–140,863,405	22.38
6: 95867927	FRAS1	94,711,652–95,055,569	33.89
	PAQR3	95,409,078–95,441,932	22.86
	GK2	95,882,918–95,884,576	13.76
	ENSBTAG00000032034	95,908,624–95,908,893	11.44
10: 68534665	KTN1	68,238,010–68,351,879	42.59
10: 68534665	OTX2	69,458,818–69,462,865	13.60
13: 32852133	KLF6	44,945,068–44,952,151	17.28
17: 71393345	LIF	71,413,855–71,418,166	14.25
24: 29556826	SPIRE1	43,323,645–43,488,851	12.47

ISSN: 1471-2164