Fig. 2From: A cmap-enabled gene expression signature-matching approach identifies small-molecule inducers of accelerated cell senescenceRadiation- and p21-induced senescence display related gene expression patterns. Plot shows differentially expressed genes detected in radiation-induced and/or p21-induced senescence. Microarray analysis was performed comparing of MCF7GFP-IBD cells, 5 days after 6 Gy irradiation, or MCF7p21 cells, 5 days after induction with doxycycline, to untreated controls. The relative expression of all detected genes is shown, log transformed. Selected genes are labeled.Back to article page