Table 1 Most significant canonical pathways identified by IPA analysis of the shared differentially expressed genes (DEGs)
Ingenuity canonical pathways | -log(p-value) |
|---|---|
Role of BRCA1 in DNA Damage Response | 8.54 |
Role of CHK Proteins in Cell Cycle Checkpoint Control | 8.05 |
Mitotic Roles of Polo-Like Kinase | 7.54 |
Cell Cycle: G2/M DNA Damage Checkpoint Regulation | 6.06 |
Cell Cycle Control of Chromosomal Replication | 5.41 |
ATM Signaling | 5.22 |
Mismatch Repair in Eukaryotes | 5.2 |
Hereditary Breast Cancer Signaling | 4.63 |
Estrogen-mediated S-phase Entry | 4.58 |
BER pathway | 3.56 |
Cyclins and Cell Cycle Regulation | 2.91 |
β-alanine Degradation I | 2.52 |