Transcriptional profiling and pathway analysis reveal differences in pituitary gland function, morphology, and vascularization in chickens genetically selected for high or low body weight

Table 3 Top gene interaction networks containing DEGs within pituitary glands of HG and LG chickens

^aAssociated Network Functions	^b DEGs (#)	^cTotal Genes (#)
Molecular transport, inflammatory disease	30	34
Cancer, developmental disorder, lipid metabolism	29	33
Organ morphology, cellular compromise, cardiovascular system development and function	21	34
Endocrine system development and function, carbohydrate metabolism, small molecule biochemistry	16	34
Cell-to-cell signaling and interaction, cellular function and maintenance, tumor morphology	16	34

^aAs determined by Ingenuity Pathway Analysis gene interaction network prediction
^bThe number of DEGs between HG and LG birds from our dataset contained within each network
^cThe total number of genes contained within each network

ISSN: 1471-2164