aFold – using polynomial uncertainty modelling for differential gene expression estimation from RNA sequencing data

Table 1 Overiew of the used real data sets

Set name	Average library size	#Present Genes	Sample size	#DEs¹	Used for
ABRF	54,822,037	42,613	18	29,013	DE & Type I error
SEQC	66,503,428	44,931	10	17,038	DE
MAQC-II	1,421,992	11,907	14	8387	DE
Modencodefly	13,709,954	13,244	147	–	Type I error
HapMap-CEU	5,187,226	12,410	41	8	DE
Bottomly	4,904,164	13,932	21	1112	DE
PrimePCR	–	20,801	–	16,603	True DE

(−) indicates that the statistics are not applied. (1) the number of DEs represents average DEs reported by aFold, DESeq2 and Voom

ISSN: 1471-2164