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Fig. 5 | BMC Genomics

Fig. 5

From: Histone H3 lysine 4 methyltransferase is required for facultative heterochromatin at specific loci

Fig. 5

Loss of KMT1/DIM5 affects H3K4me3 distribution. (a) Stacked bar plot showing the number (x-axis) of H3K4me3-containing transcripts that have a decreased in H3K4me3 levels in ∆kmt1/∆dim-5 (p < 0.05). Transcripts are catalogued by expression changes in WT versus ∆kmt1/∆dim-5 (q < 0.05). (b) Representative gene-level plot of a locus that has a reduction in H3K4me3 in ∆kmt1/∆dim-5. H3K9me3 and H3K4me3 ChIP-seq data is shown for WT and the corresponding knockouts. Transcripts originating for either the + or – strand were separated and plotted individually. (c) The expression level of the three genes is represented as bar plots for NCU10058, NCU10059 and NCU16377 in WT, kmt2/set-1 and kmt1/dim-5 comparing expression in DD (grey) versus LP30 (black)

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