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Table 1 Comparison of SMRTseq concentrations to UHPLC-ms/m. Calculated DNA methylation concentrations from SMRTseq or UHPLC-ms/ms demonstrates that 6 mA quantification by SMRTseq is more accurate at higher levels of 6mA than when it is less abundant and SMRTseq is inaccurate when identifying 4mC

From: Sources of artifact in measurements of 6mA and 4mC abundance in eukaryotic genomic DNA

  1. # indicates measurements performed in this study, ND indicates not detectable at our limit of detection (< 0.00003% for 6 mA and < 0.00005% for 4mC), NM indicates not measured or not reported
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BMC Genomics

ISSN: 1471-2164

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