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Table 4 Biological activity of BII_Rafflesfungin

From: Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723

Fungal strain/Cell line

IC50, μM

Candida albicans ATCC 10231

2.4

Candida albicans ATCC 90028

4.6

Saccharomyces cerevisiae (BY4741)

2.7

Aspergillus fumigatus ATCC 46645

1.2

Aspergillus brasiliensis ATCC 16404

7.4

A549 lung carcinoma cells

16.5

HepG2 liver carcinoma cells

13.8

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BMC Genomics

ISSN: 1471-2164

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