Transcriptomic responses to diet quality and viral infection in Apis mellifera

BMC Genomics

Table 1 Known functions of the mapped subset of 43 DEGs in the virus main effect of our study

BeeBase ID, NCBI Gene ID	Gene Name	Known functions	Us	Galbraith
GB41545, 409187	MD-2-related lipid-recognition protein-like	Implicated in lipid recognition, particularly in the recognition of pathogen related products	N	-
GB50955, 411577	Protein argonaute-2	Interacts with small interfering RNAs to form RNA-induced silencing complexes which target and cleave transcripts that are mostly from viruses and transposons	V	V
GB48755, 727455	UBA-like domain-containing protein 2	Found in diverse proteins involved in ubiquitin/proteasome pathways	V	V
GB47407, 406132	Histone H4	Capable of affecting transcription, DNA repair, and DNA replication when post-transcriptionally modified	V	V
GB42313, 409923	Leishmanolysin-like peptidase	Encodes a protein involved in cell migration and invasion; implicated in mitotic progression in D. melanogaster	V	V
GB50813, 410127	Rho guanine nucleotide exchange factor 11	Implicated in regulation of apoptopic processes, cell growth, signal transduction, and transcription	V	V
GB54503, 411255	Thioredoxin domain-containing protein	Serves as a general protein disulphide oxidoreductase	N	-
GB53500, 100576392	Transcriptional regulator Myc-B	Regulator gene that codes for a transcription factor	V	V
GB51305, 551252	Tropomyosin-like	Related to protein involved in muscle contraction	N	N
GB50178, 726905	Cilia and flagella-associated protein 61-like	Induces components required for wild-type motility and stable assembly of motile cilia	V	V

Whether the gene was overrepresented in the virus or non-virus group is also indicated for both our study and the Galbraith study. Functionalities were extracted from Flybase, National Center for Biotechnology Information and The European Bioinformatics Institute databases

ISSN: 1471-2164