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Table 3 Ten most significantly enriched GO terms in each condition of the OR semispecies

From: The effect of Wolbachia on gene expression in Drosophila paulistorum and its implications for symbiont-induced host speciation

GO Term

Annotation

Nr Ann.a

Nr DEa

Nr Exp.a

Signif.a

Female abdomen upregulated

 GO:0045214

sarcomere organization

27

12

0.58

9.20E-14

 GO:0030239

myofibril assembly

38

18

0.82

4.90E-09

 GO:0007498

mesoderm development

74

12

1.6

4.80E-08

 GO:0006936

muscle contraction

23

10

0.5

4.50E-07

 GO:0071688

striated muscle myosin thick filament assembly

5

4

0.11

1.00E-06

 GO:0007015

actin filament organization

111

12

2.4

2.30E-06

 GO:0034446

substrate adhesion-dependent cell spreading

7

4

0.15

7.00E-06

 GO:0006941

striated muscle contraction

8

4

0.17

1.40E-05

 GO:0060361

flight

10

4

0.22

4.00E-05

 GO:0007519

skeletal muscle tissue development

7

3

0.15

0.00033

Female abdomen downregulated

 GO:0031122

cytoplasmic microtubule organization

20

5

0.31

9.80E-06

 GO:0006270

DNA replication initiation

23

5

0.35

2.10E-05

 GO:0007147

female meiosis II

5

3

0.08

3.40E-05

 GO:0007338

single fertilization

27

6

0.41

0.00019

 GO:0006277

DNA amplification

21

3

0.32

0.00023

 GO:0007280

pole cell migration

21

4

0.32

0.00025

 GO:0006013

mannose metabolic process

10

3

0.15

0.00038

 GO:0071480

cellular response to gamma radiation

10

3

0.15

0.00038

 GO:0006517

protein deglycosylation

13

3

0.2

0.00089

 GO:0048640

negative regulation of developmental growth

67

5

1.02

0.00131

Female head upregulated

 GO:0016059

deactivation of rhodopsin mediated signaling

16

3

0.04

6.60E-06

 GO:0042052

rhabdomere development

36

3

0.09

8.10E-05

 GO:0007601

visual perception

18

2

0.04

0.00083

 GO:0045494

photoreceptor cell maintenance

29

2

0.07

0.00216

 GO:0050830

defense response to Gram-positive bacterium

36

2

0.09

0.00331

 GO:2000370

positive regulation of clathrin-mediated endocytosis

5

1

0.01

0.01202

 GO:0051282

regulation of sequestering of calcium ion

5

1

0.01

0.01202

 GO:0051966

regulation of synaptic transmission, glutamatergic

5

1

0.01

0.01202

 GO:0050913

sensory perception of bitter taste

5

1

0.01

0.01202

 GO:0007604

phototransduction, UV

5

1

0.01

0.01202

Female head downregulated

 GO:0002181

cytoplasmic translation

86

28

1.78

9.10E-27

 GO:0055114

oxidation-reduction process

472

37

9.78

3.60E-10

 GO:0046653

tetrahydrofolate metabolic process

5

4

0.1

8.70E-07

 GO:0000028

ribosomal small subunit assembly

12

5

0.25

2.50E-06

 GO:0006414

translational elongation

19

5

0.39

3.30E-05

 GO:0006730

one-carbon metabolic process

14

4

0.29

0.00015

 GO:0006164

purine nucleotide biosynthetic process

83

5

1.72

0.00042

 GO:0006635

fatty acid beta-oxidation

31

5

0.64

0.00134

 GO:0017085

response to insecticide

12

3

0.25

0.00167

 GO:0009620

response to fungus

54

4

1.12

0.00214

Male abdomen upregulated

 GO:0045214

sarcomere organization

27

9

0.27

3.00E-12

 GO:0030239

myofibril assembly

38

14

0.39

6.50E-09

 GO:0014866

skeletal myofibril assembly

7

4

0.07

3.40E-07

 GO:0006936

muscle contraction

23

8

0.23

9.80E-07

 GO:0060361

flight

10

4

0.1

2.00E-06

 GO:0007629

flight behavior

25

5

0.25

4.30E-06

 GO:0007498

mesoderm development

74

7

0.75

9.00E-06

 GO:0071688

striated muscle myosin thick filament assembly

5

3

0.05

1.00E-05

 GO:0007015

actin filament organization

111

8

1.13

1.60E-05

 GO:0006099

tricarboxylic acid cycle

34

5

0.35

2.10E-05

Male abdomen downregulated

 GO:0032504

multicellular organism reproduction

943

35

23.13

6.50E-16

 GO:0055114

oxidation-reduction process

472

37

11.58

5.50E-11

 GO:0006508

proteolysis

677

33

16.61

1.50E-06

 GO:0009631

cold acclimation

8

4

0.2

2.30E-05

 GO:0006629

lipid metabolic process

370

28

9.08

3.30E-05

 GO:0042364

water-soluble vitamin biosynthetic process

7

3

0.17

0.00047

 GO:0042761

very long-chain fatty acid biosynthetic process

16

4

0.39

0.00051

 GO:0045434

negative regulation of female receptivity,postmating

8

3

0.2

0.00074

 GO:0006465

signal peptide processing

8

3

0.2

0.00074

 GO:0005975

carbohydrate metabolic process

410

22

10.06

0.00187

Male head upregulated

 GO:0055093

response to hyperoxia

7

1

0.01

0.0053

 GO:0019731

antibacterial humoral response

28

1

0.02

0.0212

 GO:0045793

positive regulation of cell size

29

1

0.02

0.0219

 GO:0042052

rhabdomere development

36

1

0.03

0.0271

 GO:0050830

defense response to Gram-positive bacterium

36

1

0.03

0.0271

 GO:0030307

positive regulation of cell growth

40

1

0.03

0.0301

 GO:0008286

insulin receptor signaling pathway

42

1

0.03

0.0316

 GO:0018105

peptidyl-serine phosphorylation

42

1

0.03

0.0316

 GO:0040018

positive regulation of multicellular organism

44

1

0.03

0.0331

 GO:0046620

regulation of organ growth

49

1

0.04

0.0368

Male head downregulated

 GO:0055114

oxidation-reduction process

472

45

10.14

4.40E-19

 GO:1901606

alpha-amino acid catabolic process

35

7

0.75

2.10E-05  

 GO:0046653

tetrahydrofolate metabolic process

5

3

0.11

9.40E-05

 GO:0009620

response to fungus

54

5

1.16

0.00013

 GO:0006730

one-carbon metabolic process

14

4

0.3

0.00017

 GO:0019236

response to pheromone

15

4

0.32

0.00023

 GO:0042559

pteridine-containing compound biosynthetic process

7

3

0.15

0.00032

 GO:0072329

monocarboxylic acid catabolic process

40

3

0.86

0.00046

 GO:0005977

glycogen metabolic process

15

5

0.32

0.00049

 GO:0006098

pentose-phosphate shunt

8

3

0.17

0.0005

  1. aNr Ann. Number of times a GO term appears in the reference gene universe. Nr DE Number of DE genes which are annotated with the GO term. Nr Exp. Number of times a GO term would be expected to appear in the DE genes dataset. Signif Significance value in Fishers’ test