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Table 3 Gene lists of the most important candidates for drug resistance in P.aeruginosa

From: Identifying genetic determinants of complex phenotypes from whole genome sequence data

Drug Setting 1 Setting 2 Setting 3
Ciprofloxacin trpI, transcriptional regulator TrpI hypothetical protein trpI, transcriptional regulator TrpI
  lysin domain-containing protein HIS/PHE ammonia-lyase tag, DNA-3-methylad. glycosidase I
  tag, DNA-3-methylad. glycosidase I LysR family transcriptional regulator lysin domain-containing protein
  recF, recombination protein F   glutamine synthetase
  D,D-heptose 1,7-bisphos. phosphatase   hypothetical protein
Ceftazidime hemolysin activ./secret. prot hypothetical protein (PA_40040) hemolysin activ./secret. prot
  hypothetical protein (PA_40040) sensor/response regulator hybrid hypothetical protein (PA_40040)
  gyrB, DNA gyrase subunit B   gyrB, DNA gyrase subunit B
    hemagglutinin
    recQ, ATP-depend. DNA helicase
Gentamicin Rossmann fold nucleotide-bind. prot. sbrR, SbrR tonB2, hypothetical protein
  gyrB, DNA gyrase subunit B tonB2, hypothetical protein hemagglutinin
  hemagglutinin hemagglutinin sbrR, SbrR
  acyltransferase tufA, elongation factor Tu hemolysin activ./secret. prot
  tonB2, hypothetical protein hemolysin activ./secret. prot  
  nirN, c-type cytochrome   
  1. Shown are the genes identified in all four runs under the four settings defined in Table 2. For each drug, the genes identified in all three settings are highlighted (boldface), as well as those found in two out of the three settings (italics). Gene names that are underlined (setting 1 only) are those identified during the cross-validation experiment, under both chunk sizes