From: Relation between DNA ionization potentials, single base substitutions and pathogenic variants
X | Doublets XN | Triplets NXN | Quadruplets NXNN | Quintuplets NNXNN | Sextuplets NNXNNN |
---|---|---|---|---|---|
Missense mutations in exons | |||||
All | -0.6 | -1.1 | -1.1 | -1.3 | -1.5 |
Synonymous mutations in exons | |||||
All | -1.4 | -1.8 | -2.1 | -2.4 | -2.6 |
Mutations in introns | |||||
All | -1.8 | -3.7 | -3.7 | -4.4 | -5.3 |
Mutations in UTRs | |||||
All | -0.9 | -1.4 | -1.4 | -1.5 | -1.7 |