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Fig. 2 | BMC Genomics

Fig. 2

From: A catalog of CasX genome editing sites in common model organisms

Fig. 2

Hamming distance for editing targets amongst Ensembl mouse strains. Shown is the Hamming distance between sites for the GRCm38 reference (denoted Mus musculus), and genomes of 15 strains available via Ensembl. The matrix was ordered by calculating the hierarchical clustering of the distances with complete linkage. The strains CAST/EiJ and PWK/PhJ were the furthest from the GRCm38 reference among the tested strains, though all had some degree of difference. Those two strains in particular might require site annotations for their specific genomes rather than site selection from the general mouse reference

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