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Fig. 1 | BMC Genomics

Fig. 1

From: Alternative polyadenylation produces multiple 3’ untranslated regions of odorant receptor mRNAs in mouse olfactory sensory neurons

Fig. 1

Comparison between available annotations for Olfr1507 and Olfr15 3’UTR isoforms and RNA-Seq raw data. a Upper panel. 3’UTRs from Ibarra-Soria et al. [26] RNA-Seq study (Dataset S6 in this paper). Center panel. 3’UTRs from Shum et al. [27] RNA-Seq study (File 013 Additional File 26 Table S3 in this paper). An alternative 3’UTR for Olfr15 due to 3′ length variation is mentioned (File 010 Additional File 3: Table S2 in [27]) but not described. Bottom panel. 3’UTRs in Ensembl release 89 [45].*: 3’UTRs deduced from RNA-Seq annotation (raw data in [26]) by the Havana project: ENSMUST00000206062.3 for Olfr1507; ENSMUST00000214590.1/ENSMUST00000214238.1 for Olfr15. Black vertical box: CDS end; black horizontal bar: 3’UTR. b Exon coverage, linear scale (top panel) and log scale (bottom panel), from olfactory mucosa RNA-Seq data of 3 adult male mice (male_IS2014, from [26]). Dashed lines indicate sustained drop of coverage that may be visually interpreted as 3′ ends; bold dashed lines indicate quantitatively major isoforms. Olfr1507 coverage suggests a short major 3’UTR isoform (S, previously described in a), and at least 2 additional minor 3’UTR isoforms with longer 3’UTRs (not described in a). Olfr15 coverage suggests 2 major 3’UTR isoforms (shorter than the 3’UTRs previously described in a), and a long minor 3’UTR isoform (L, previously described in a)

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