Fig. 3

Patterns of a string of single-nucleosome histone modification signals near TSS. (a) Patterns of histone modification codes near TSS by the K-means clustering. Each color represents one single or multivalent histone modification mark in each nucleosome from combined analysis of all five histone marks shown in Fig. 1c. (b) Percentages of genes with and without histone marks from the clustering analysis in (a). (c) The top 5 canonical pathways could be regulated by genes in each cluster using Ingenuity