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Table 1 Top five loci associated with heifer conception rate at first service (HCR1)

From: Validation of 46 loci associated with female fertility traits in cattle

BTAa

BP Positionb

SNP IDc

Modeld

P-valuee

1

3,546,098 (4,253,950)

rs136767715

Dominant

3.14 × 10−19

1

14,740,447 (15,273,288)

rs109845303

Recessive

3.31 × 10−11

3

37,781,561 (37,660,099)

rs137663076

Recessive

1.10 × 10−10

4

37,235,676 (37,056,340), 37,618,902 (37,439,721)

rs133417267, rs43388620

Additive, Dominant, Recessive

6.93 × 10− 21, 6.93 × 10− 21, 5.18 × 10− 09

5

35,925,646 (35,745,274)

rs135774967

Recessive

1.39 × 10− 10

10

37,205,266 (37,088,125)

rs135421839

Additive

3.15 × 10− 13

10

59,882,200 (59,695,958)

rs110617366

Additive, Dominant

7.12 × 10−18, 1.34 × 10− 23

11

2,125,437 (2,159,226)

rs133812771

Dominant

1.34 × 10− 20

20

57,113,135 (57,038,642)

rs41956232

Additive

1.15 × 10−13

24

50,503,943 (50,038,623)

rs110770205

Recessive

1.74 × 10−13

27

21,375,791 (22,307,598)

rs132728892

Additive, Dominant

8.35 × 10−52, 8.35 × 10− 52

  1. a Chromosome location of the locus
  2. b Single nucleotide polymorphism (SNP) location as measured by numbered nucleotides in reference to the UMD 3.1 genome assembly (http://bovinegenome.org/?q=node/61; accessed 15 September 2016) or the ARS-UCD 1.2 genome assembly (https://www.animalgenome.org/repository/cattle/UMC_bovine_coordinates/; accessed 19 September 2018) in parentheses
  3. c The most significant SNP in the locus associated with heifer conception rate as identified by rs number which is a reference number assigned to markers submitted to the National Center for Biotechnology Information SNP database (https://www.ncbi.nlm.nih.gov/projects/SNP/; accessed 9 March 2016)
  4. d Genome-wide association model
  5. e Significance (P-value) of the most significant SNP associated with heifer conception rate