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Table 1 Top five loci associated with heifer conception rate at first service (HCR1)

From: Validation of 46 loci associated with female fertility traits in cattle

BTAa BP Positionb SNP IDc Modeld P-valuee
1 3,546,098 (4,253,950) rs136767715 Dominant 3.14 × 10−19
1 14,740,447 (15,273,288) rs109845303 Recessive 3.31 × 10−11
3 37,781,561 (37,660,099) rs137663076 Recessive 1.10 × 10−10
4 37,235,676 (37,056,340), 37,618,902 (37,439,721) rs133417267, rs43388620 Additive, Dominant, Recessive 6.93 × 10− 21, 6.93 × 10− 21, 5.18 × 10− 09
5 35,925,646 (35,745,274) rs135774967 Recessive 1.39 × 10− 10
10 37,205,266 (37,088,125) rs135421839 Additive 3.15 × 10− 13
10 59,882,200 (59,695,958) rs110617366 Additive, Dominant 7.12 × 10−18, 1.34 × 10− 23
11 2,125,437 (2,159,226) rs133812771 Dominant 1.34 × 10− 20
20 57,113,135 (57,038,642) rs41956232 Additive 1.15 × 10−13
24 50,503,943 (50,038,623) rs110770205 Recessive 1.74 × 10−13
27 21,375,791 (22,307,598) rs132728892 Additive, Dominant 8.35 × 10−52, 8.35 × 10− 52
  1. a Chromosome location of the locus
  2. b Single nucleotide polymorphism (SNP) location as measured by numbered nucleotides in reference to the UMD 3.1 genome assembly (http://bovinegenome.org/?q=node/61; accessed 15 September 2016) or the ARS-UCD 1.2 genome assembly (https://www.animalgenome.org/repository/cattle/UMC_bovine_coordinates/; accessed 19 September 2018) in parentheses
  3. c The most significant SNP in the locus associated with heifer conception rate as identified by rs number which is a reference number assigned to markers submitted to the National Center for Biotechnology Information SNP database (https://www.ncbi.nlm.nih.gov/projects/SNP/; accessed 9 March 2016)
  4. d Genome-wide association model
  5. e Significance (P-value) of the most significant SNP associated with heifer conception rate