Validation of 46 loci associated with female fertility traits in cattle

Kiser, Jennifer N.; Keuter, Elizabeth M.; Seabury, Christopher M.; Neupane, Mahesh; Moraes, Joao G. N.; Dalton, Joseph; Burns, Gregory W.; Spencer, Thomas E.; Neibergs, Holly L.

doi:10.1186/s12864-019-5935-3

BMC Genomics

Table 5 Validated loci associated with cattle fertility

From: Validation of 46 loci associated with female fertility traits in cattle

BTA^a	Region (Mb)^b	Previous Studies^c	Previous Phenotype(s)^d	Previous Breeds^e	Current Study Phenotype(s)^f
1	61–62	1 [37]	AISC	Holstein^N	HCR1 & TBRD
1	68–69	1 [37]	AISH	Holstein^N	HCR1 & TBRD
1	147–148	1 [37]	AISC	Holstein^N	HCR1 & TBRD
2	53–54	1 [37]	AISC	Holstein^N	HCR1 & TBRD
2	123–124	1 [37]	AISH	Holstein^N	HCR1 & TBRD
2	136–137	1 [33]	CI	Holstein^It	HCR1 & TBRD
3	90–91	1 [37]	AISC	Holstein^N	HCR1 & TBRD
4	29–30	1 [37]	AISC	Holstein^N	TBRD
4	37–38	1 [40]	Reproduction	Brangus^U, Brahman^A, Tropical Composite^A	HCR1 & TBRD
5	64–65	1 [40]	Reproduction	Brangus^U, Brahman^A, Tropical Composite^A	TBRD
5	88–89	1 [36]	ICF	Holstein^Ca	HCR1 & TBRD
5	107–108	2 [19, 37]	CI [19]; IFLC & ICF [37]	Holstein^A,I,N, Jersey^A	HCR1 & TBRD
5	112–113	1 [37]	AISC	Holstein^N	TBRD
5	116–117	1 [33, 37]	NRRC [33]; AISC [37]	Holstein^It,N	HCR1
5	118–119	1 [37]	AISC	Holstein^N	TBRD
6	23–24	1 [38]	DO & SC	Holstein^U	HCR1 & TBRD
6	92–93	2 [19, 37]	CI [19]; FTI & ICF [37]	Holstein^A,I,N, Jersey^A	HCR1 & TBRD
7	43–44	1 [37]	AISC	Holstein^N	TBRD
8	20–21	1 [37]	AISC, AISH	Holstein^N	HCR1 & TBRD
8	91–92	1 [33]	CI	Holstein^It	TBRD
11	8–9	1 [37]	AISC	Holstein^N	TBRD
13	45–46	1 [37]	AISC	Holstein^N	TBRD
14	1–2	3 [19, 37]	CI [19]; AISC, FTI, IFLC, & NRRC [37]; HCR & CCR	Holstein^A,I,N,U, Jersey^A	TBRD
14	82–83	2 [33, 37]	AISH [37]; NRRC [33]	Holstein^It,N	HCR1
16	21–22	1 [34]	P28	Angus crossbreed^U	HCR1 & TBRD
16	36–37	1 [40]	Reproduction	Brangus^U, Brahman^A, Tropical Composite^A	HCR1 & TBRD
17	3–4	2 [19, 37]	CI [19]; AISH & IFLC [37]	Holstein^A,I,N, Jersey^A	HCR1 & TBRD
17	14–15	1 [37]	AISC	Holstein^N	TBRD
17	72–73	2 [19, 37]	CI [19]; NRRC [37]	Holstein^A,I,N, Jersey^A	HCR1 & TBRD
18	61–62	2 [19]	CI [19]; DPR	Holstein^A,I,N, Jersey^A	HCR1 & TBRD
18	62–63	3 [19, 35, 37]	CI [19]; FTI & IFLC [37]; P42 [35]	Holstein^A,I,N, Jersey^A	HCR1 & TBRD
18	62–63	3 [19, 35, 37]	CI [19]; FTI & IFLC [37]; P42 [35]	Holstein^A,I,N, Jersey^A	HCR1 & TBRD
18	47–48	1 [33]	DFS	Holstein^It	TBRD
20	27–28	1 [37]	AISC	Holstein^N	TBRD
21	54–55	2 [19, 37]	CI [19]; NRRC [37]	Holstein^A,I,N, Jersey^A	HCR1
22	49–50	2 [19, 37]	CI [19]; ICF [37]	Holstein^A,I,N, Jersey^A	TBRD
22	49–50	2 [19, 37]	CI [19]; ICF [37]	Holstein^A,I,N, Jersey^A	TBRD
23	50–51	1 [38]	CR1	Holstein^Ca,N	TBRD
24	60–61	1 [37]	AISC	Holstein^N	TBRD
26	27–28	1 [37]	AISC	Holstein^N	HCR1 & TBRD
26	34–35	2 [19, 37]	CI [19]^; AISC, NRRC, & NRRH [37]	Holstein^A,I,N, Jersey^A	HCR1
26	35–36	1 [37]	AISC	Holstein^N	HCR1
28	8–9	1 [37]	AISC	Holstein^N	HCR1 & TBRD
29	14–15	1 [37]	AISH	Holstein^N	TBRD
29	16–17	1 [37]	AISH	Holstein^N	TBRD
29	50–51	1 [37]	AISC	Holstein^N	TBRD

^a Bos taurus chromosome (BTA) location of the locus
^b Region associated locus is located in (in Mb) as measured by numbered nucleotides in reference to the UMD 3.1 genome assembly (http://bovinegenome.org/?q=node/61; accessed 15 September 2016)
^c Number of previous studies locus previous associated in is listed. The citation number for each study is listed in superscript brackets
^d Traits previously associated with loci abbreviated as follows: AISC number of inseminations to conception in cows, AISC number of inseminations to conception in heifers, CI calving interval, CCR cow conception rate, CR1 conception rate to first insemination in cows, DFS days to first service, DO days open, DPR daughter pregnancy rate, FTI fertility index, HCR heifer conception rate, ICF interval (in days) from calving to first insemination, IFLC days from first to last insemination in cows, NRRC 56 day non return rate in cows, NRRH 56 day non return rate in heifers, P28 pregnancy success at day 28 post embryo transfer, P42 pregnancy success within first 42 days of mating, SC services per conception. If multiple traits are listed from different studies the citation number for study is listed in superscript brackets
^e Cattle breeds loci were previously identified are listed with the country or region the population was from indicated in superscript as follows: Australian - A; Canadian - Ca; Chinese - C, Irish - I; Italian - It; Nordic - N; United States - U
^f Phenotype of the current study the loci was associated with: conception rate at first AI service - HCR1; number of breedings to conception - TBRD

Back to article page

ISSN: 1471-2164

Contact us

Submission enquiries: bmcgenomics@biomedcentral.com
General enquiries: ORSupport@springernature.com