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Table 1 Genomic location, amino acid length of the main isoform, number of biochemically characterized active sites, and cellular localization of human histone deacetylases

From: Promoter conservation in HDACs points to functional implications

  ChmProtein length of main isoform (aa)Number of active sitesPresent in nucleusPresent in cytoplasm
Class IHDAC11p34.14821PN (If present, results in axonal damage [2])
HDAC26q214881PN
HDAC35q31.24281PP
HDAC8Xq133771PP [3]
Class IIAHDAC42q37.210841PP
HDAC517q2111221PP
HDAC712q13.19521PP
HDAC97p21.110111PP
Class IIBHDAC6Xp11.2312152PP
HDAC1022q13.316691PP
Class IVHDAC113p25.13471PP
  1. Data from the NCBI Gene database, and localization data from [1], except where shown. P present, N Not present