Table 4 Identification of differentially expressed miRNAs and their targets in adult ovaries of Wolbachia-infected flies relative to uninfected ones
miRNA | Log2 Fold difference (Log2 Dmel wMel/ Dmel T) | Target gene | Fold difference (Log2 Dmel wMel/ Dmel T) | Biological functions of target genes |
|---|---|---|---|---|
dme-miR-982-5p | 3.9511 | sosie | −1.1911 | Ovarian follicle cell migration |
CG9411 | 2.7156 | −//− | ||
dme-miR-983-5p | 2.8377 | blanks | 2.0137 | Regulation of chromatin silencing |
dme-miR-982-3p | 1.8142 | nompC | −5.7343 | Cellular response to mechanical stimulus |
Mal-A7 | 3.5326 | Carbohydrate metabolic process | ||
tut | 1.4346 | Negative regulation of translation | ||
dme-miR-984-5p | 1.7784 | – | ||
dme-miR-318-3p | 1.3118 | Mlc2 | −1.1691 | Muscle system process, myofibril assembly |
Oamb | 1.0821 | Ovulation, male courtship behavior | ||
sosie | −1.1911 | Ovarian follicle cell migration | ||
dme-miR-956-3p | 1.2088 | tipE | 1.711 | Regulation of sodium ion transport |
nolo | −1.7481 | Ventral cord development | ||
CG42324 | 1.0045 | −//− | ||
dme-miR-983-3p | 1.1192 | scro | 1.5012 | Dendrite morphogenesis |
Rab3-GEF | 1.1454 | Regulation of cell cycle | ||
Neurochondrin | −1.0955 | Muscle system process | ||
CG32816 | 1.4094 | −//− |