Skip to main content

Table 1 Significance of DMRs overlapping genomic features

From: Genome-wide effects of social status on DNA methylation in the brain of a cichlid fish, Astatotilapia burtoni

A

body

p-val

5′ reg

p-val

3′ reg

p-val

 DMRs

522

<1e-4

147

0.027

145

0.042

  > 1 gene

15

0.15

20

0.46

19

0.61

 genes

484

<1e-4

166

0.057

162

0.11

  > 1 DMR

42

0.042

2

0.47

5

0.053

  coding

469

<1e-4

150

0.12

156

0.053

  lncRNA

15

0.43

16

0.055

6

0.94

B

TE

<null p-val

CNE

>null p-val

  

 DMRs

111

<1e-4

44

<1e-4

  

 DMRs (> 1 hit)

29

0.006

3

0.29

  

 hits

146

<1e-4

48

0.001

  

  +gene body

65

<1e-4

28

<1e-4

  

  + 5′ region

34

0.46

6

0.0093

  

  + 3′ region

33

0.34

3

0.28

  
  1. A: Numbers of DMRs in gene bodies and regulatory regions with p-values (columns). Rows are the numbers of: DMRs overlapping at least one (1) or more (2) genes, genes with at least one (3) or more (4) DMRs, protein-coding genes (5), and long-non-coding RNAs (6). P-values are defined as the fraction of nullDMR sets with as many or more overlaps as the real DMRs and p-values < 0.1 are bolded (see Methods). The 3′ regulatory region-lncRNA p-value is italicized because this number was actually lower than expected since only ~ 6% of the nullDMR sets had fewer hits in 3′ regulatory regions of lncRNAs
  2. B: Numbers of DMRs containing transposable elements (TEs) and conserved non-coding elements (CNEs) with p-values (columns). Rows are the numbers of: DMRs overlapping at least one (1) or more (2) TE/CNE, TE/CNEs in a DMR (3), TE/CNEs in a DMR that also overlapped a gene body (4) or regulatory region (5,6). P-values reflect the fraction of nullDMR sets with fewer (TEs) or more (CNEs) hits than the actual DMRs