Table 3 Calculated tMRCAs values for HEV partial ORF1 (852 nt at the 3′ end)
From: Comprehensive analysis of genetic and evolutionary features of the hepatitis E virus
tMRCA | Strict clock | Relaxed uncorrelated clock | ||||
|---|---|---|---|---|---|---|
Lognormal | Exponential | |||||
| Â | Mean | 95% HPD | Mean | 95% HPD | Mean | 95% HPD |
Genotype clades | ||||||
 1, 2, 3 and 4 | 782.26 | 617.34–952.01 | 752.37 | 539.76–995.17 | 643.212 | 322.24–1044.84 |
 1 and 2 | 528.66 | 397.69–675.96 | 504.74 | 311.71–713.90 | 341.627 | 133.62–683.44 |
 3 and 4 | 718.1 | 569.82–863.28 | 662.37 | 461.54–871.85 | 549.387 | 273.75–905.95 |
 1 | 97.96 | 82.12–114.74 | 106.80 | 79.28–137.49 | 121.726 | 66.23–197.544 |
 3 | 247.12 | 196.69–299.17 | 264.73 | 181.02364.46 | 259.124 | 117.84–450.49 |
 4 | 156.88 | 130.49–182.22 | 160.96 | 120.04–204.18 | 144.828 | 77.24–226.75 |
Evolutionary rate (×10 −3 sub/site/year) | 1.14 | 1–1.3 | 1.28 | 0.89–1.66 | 1.76 | 1.14–2.39 |