Table 1 Crosses used to produce mice for EM/HD mapping
From: Heart disease in a mutant mouse model of spontaneous eosinophilic myocarditis maps to three loci
Recombinant Cross | # litters | ♂, affected | ♀, affected | total, affected | % affected |
|---|---|---|---|---|---|
(B6 x A/JHD) F2 | 10 15 | 54, 0 84, 0 | 48, 0 97, 0 | 102, 0 181, 0 | 0 0 |
(B6 x A/JHD) N2 | 5 | 21, 0 | 29, 1 | 50, 1 | 2.0 |
(S1 x A/JHD) F2 | 32 | 123, 0 | 143, 2 | 266, 2 | 0.75 |
(D2 x A/JHD) F2 (C5 deficient) | 58 | 262, 9 | 248, 6 | 510, 15 | 2.9 |
(D2 x A/JHD) N2 (C5 deficient) | 26 | 114, 7 | 122, 13 | 236, 20 | 8.5 |
(SJ x A/JHD) F2 (Dysf deficient) | 31 | 148, 12 | 139, 10 | 287, 22 | 7.7 |
(SJ x A/JHD) N2 (Dysf deficient) | 13 | 42, 8 | 56, 9 | 98, 17 | 17.3 |