name | chromosome | start (Mb) | end (Mb) | number of mi-eQTL | Overlapping Addiction-related bQTL |
---|
Hotspot-chr7 | 7 | 37.8 | 64.6 | 22 | Alcohol preference [29] |
Hotspot-chr10 | 10 | 23.6 | 25.3 | 8 | Morphine Preference [30] |
Hotspot-chr11 | 11 | 93.4 | 102.6 | 13 | LORR [31] |
Hotspot-chrX | x | 66.6 | 82.2 | 9 | No Addiction Related |
- Hotspots were evaluated using mi-eQTL determined at a Bonferroni corrected threshold of 0.05 (4e-8) and hotspot significance of 0.05 after Bonferroni adjustment for number of bins tested. Overlapping bQTLs were determined by results of the MGI Phenotypes, Alleles, & Disease Models Search