Fig. 1
From: Rapid adaptation of signaling networks in the fungal pathogen Magnaporthe oryzae
The Magnaporthe oryzae HOG signaling cascade. The two-component hybrid histidine kinases MoSln1p and MoHik1p are the sensors for environmental changes. Under normal environmental conditions, the phosphotransferase protein MoYpd1p transfers the phosphate to the response regulator MoSsk1p. Consequently, the phosphorelay system MoSln1p-MoHik1p-MoYpd1p-MoSsk1p is active and the MAPK cascade MoSsk2p-MoPbs2p-MoHog1p is inactive (left). High osmolarity or salt stress leads to dephosphorylation of the sensor kinases MoSln1p and/or MoHik1p resulting in a decrease of MoSsk1p-phosphorylation. Lower phosphorylation-levels at MoSsk2p activate the MAPK cascade MoSsk2p-MoPbs2p-MoHog1p, MoHog1p translocates into the nucleus and activates the cellular reactions