Table 10 Indicative biological pathways associated with the candidate aging genes
Index | Name | P-value | Adjusted p-value | Z-score | Combined score |
|---|---|---|---|---|---|
1 | Pathways in cancer_Homo sapiens_hsa05200 | 4.07e-41 | 1.19e-38 | −2.11 | 196.21 |
2 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.91e-31 | 2.78e-29 | −1.99 | 140.58 |
3 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 3.24e-30 | 3.15e-28 | −1.9 | 128.92 |
4 | Endocytosis_Homo sapiens_hsa04144 | 1.19e-28 | 8.70e-27 | −1.89 | 121.38 |
5 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 4.30e-26 | 2.51e-24 | −1.82 | 106.42 |
6 | HTLV-I infection_Homo sapiens_hsa05166 | 1.01e-25 | 4.21e-24 | −1.79 | 103.2 |
7 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 7.55e-26 | 3.68e-24 | −1.69 | 98.04 |
8 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.24e-25 | 4.54e-24 | −1.61 | 92.36 |
9 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.79e-22 | 4.96e-21 | −1.83 | 91.82 |
10 | Focal adhesion_Homo sapiens_hsa04510 | 1.12e-22 | 3.63e-21 | −1.72 | 86.98 |