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Table 10 Indicative biological pathways associated with the candidate aging genes

From: Genome-wide prediction and prioritization of human aging genes by data fusion: a machine learning approach

IndexNameP-valueAdjusted p-valueZ-scoreCombined score
1Pathways in cancer_Homo sapiens_hsa052004.07e-411.19e-38−2.11196.21
2Proteoglycans in cancer_Homo sapiens_hsa052051.91e-312.78e-29−1.99140.58
3Epstein-Barr virus infection_Homo sapiens_hsa051693.24e-303.15e-28−1.9128.92
4Endocytosis_Homo sapiens_hsa041441.19e-288.70e-27−1.89121.38
5Regulation of actin cytoskeleton_Homo sapiens_hsa048104.30e-262.51e-24−1.82106.42
6HTLV-I infection_Homo sapiens_hsa051661.01e-254.21e-24−1.79103.2
7Protein processing in endoplasmic reticulum_Homo sapiens_hsa041417.55e-263.68e-24−1.6998.04
8Herpes simplex infection_Homo sapiens_hsa051681.24e-254.54e-24−1.6192.36
9PI3K-Akt signaling pathway_Homo sapiens_hsa041511.79e-224.96e-21−1.8391.82
10Focal adhesion_Homo sapiens_hsa045101.12e-223.63e-21−1.7286.98