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Fig. 2 | BMC Genomics

Fig. 2

From: Detecting circular RNA from high-throughput sequence data with de Bruijn graph

Fig. 2

Five exons are in the genome (top left). Back splicing occurs from exon 4 to exon 2, which generates a circular RNA (top right). The bidirectional de Bruijn graph (bottom left) is built from the k-mers from each exon in the genome, where each exon is represented by the path with the same color in graph. The dotted line represents a RNA reads which supports the presence of circRNA case: the starting part of the read overlaps with the ending part of exon 4, and the ending part of the read overlaps with the starting part of exon 2

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