Fig. 2From: Detecting circular RNA from high-throughput sequence data with de Bruijn graphFive exons are in the genome (top left). Back splicing occurs from exon 4 to exon 2, which generates a circular RNA (top right). The bidirectional de Bruijn graph (bottom left) is built from the k-mers from each exon in the genome, where each exon is represented by the path with the same color in graph. The dotted line represents a RNA reads which supports the presence of circRNA case: the starting part of the read overlaps with the ending part of exon 4, and the ending part of the read overlaps with the starting part of exon 2Back to article page