Microevolution within ST11 group Clostridioides difficile isolates through mobile genetic elements based on complete genome sequencing

Table 2 Transposons and conjugative transposons analyzed in this study

Transposons	Referenced Isolates	Reference					Isolate 10,010		Isolate 12,038		Isolate 21,062		Common ORF^a
Transposons	Referenced Isolates	ORF	Size (kb)	Strat-end	GC%	Specific gene	ORF	enzymes	ORF	enzymes	ORF	enzymes	Common ORF^a
CTn1	CD630	32	28.9	CD0355–0386	38.6	Xis, tyro-integrase	24	transposase	24	transposase	24	transposase	10
CTn2	CD630	36	42.2	CD0408–0436	35.1	seri-rebombinase	21	N	21	N	1	DNA helicase	13
Tn5397	CD630	19	20.7	CD0496–0511	38.3	tndX, tetM, group II intron	N	N	N	N	11	tetM	9
CTn4	CD630	28	30.5	CD1091–1118	46.6	Xis, int, transposase	28	Xis, int, transposase	28	Xis, int, transposase	28	Xis, int, transposase	13
CTn5	CD630	40	45.6	CD1845–1878	32.7		35		36		N	N	25
CTn6 (novel)	CD630	26	21.3	CD3326–3348	42.8	tyrointegrase	11	N	12	N	12	N	2
CTn7	CD630	30	29.2	CD3370–3392	40.9	seri-rebombinase	31	seri	31	seri	19	N	5
Tn6103	R20291		84.9	1740–1809	41.2	rebombinase
Tn916		24	18			tetM, Xis, int	1	integrase	1	integrase	13	tetM, transposase	11
Tn5398	CD630	17	9.6	CD2001-2010b	35.4	ermB	7	N	7	N	7	N	5
Tn4453a/b	W1	7	6.3	Tnpx-tnpw		catD	1	helicase	1	helicase	10	N	3

ISSN: 1471-2164